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3aaeb96033%Utilising adeno-associated virus (AAV) to deliver CRISPR/Cas has enhanced the generation of knock-out mice, but single-AAV delivery of Cas and homology-directed-repair (HDR) templates in livestock rem…
1f0fde2633%Utilising adeno-associated virus (AAV) to deliver CRISPR/Cas has enhanced the generation of knock-out mice, but single-AAV delivery of Cas and homology-directed-repair (HDR) templates in livestock rem…
01b9388c29%To investigate the effect of TMEM175 on bone marrow-derived macrophages, bone marrow-derived macrophages from WT or Tmem175flox/flox Lyz2-Cre+/- mice were cultured. The cells were then lysed for RNA-s…
1edabb1229%To investigate the transcriptome changes of BMDM-T cell co-culture system, spleen lyphocytes were cultured with WT or Tmem175-/- BMDMs in 1640 supplied with FBS, m-CSF, and IL-2 for 48 hours. Tumor an…
b1d1125e26%This SuperSeries is composed of the SubSeries listed below.
01c51ca525%This SuperSeries is composed of the SubSeries listed below.
569cc67224%Mosquitoes serve as medically significant vectors for transmitting various arboviruses. The mosquito midgut is both the digestive organ and primary infection site via viral bloodmeals, and the midgut…
a23af49324%The mineral dust-induced gene (mdig, also called as MINA or RIOX2) is upregulated in breast cancer and predicts poor overall survival of breast cancer patients. Our studies suggested the anti-metastas…
bf49dbe724%A 10X Genomics scRNAseq of Tmem175-/- and WT B16-F10 lung matastatic model. The main purpose of this research is to explore the transcriptome changes in different immune cells.
989bce0623%To investigate the effect of the HER1, we performed RNA-seq and differential expression analyses on stigmas from WT and the her1 mutant.
625f1aa423%This SuperSeries is composed of the SubSeries listed below.
b6747e6023%A key mechanism of malignant cell evasion from anti-tumor immunity centers on tryptophan metabolism by indole-2,3-dioxygenase (IDO1). By degrading tryptophan, IDO1 impairs anti-tumor T cell responses,…
cac0380c22%Assessing anti-tumor immune responses and immune microenvironment alterations in central nervous system (CNS) neoplasms like brain tumors and leptomeningeal disease (LMD) provides prognostic insights…
f2edaa2822%Single-cell RNA sequencing revealed the increased abundance of some cell types, such as intestinal fibroblasts, in the CD-PFD rectal mucosa relative to CD. Within the stromal subset, the lamina propri…
325cf92c22%Single-cell RNA sequencing revealed the increased abundance of some cell types, such as intestinal fibroblasts, in the CD-PFD rectal mucosa relative to CD. Within the stromal subset, the lamina propri…
de0c44a822%Mice bearing intracranial GL261‑CAR tumors were treated intratumorally with PBS (control), oAd, or oAd‑mCD47/PD‑L1‑mIL‑12 (1 × 109 pfu). Tumors were harvested three days after the second viral injecti…
a204067d22%The mineral dust-induced gene (mdig, also called as MINA or RIOX2) is upregulated in breast cancer and predicts poor overall survival of breast cancer patients. Our studies suggested the anti-metastas…
c55d92ef21%The formation and homeostatic maintenance of cranial sutures rely on cellular activities within the suture mesenchyme. Mesenchymal stem cells in this niche are characterized by self-renewal capacity a…
df63dcd521%Perianal fistulizing disease (PFD) is a complication that affects about 20% of Crohn’s disease (CD) patients and whose etiology remains unknown. To identify predisposing events driving fistula formati…
1fd9d0c421%Small cell lung cancer (SCLC) is characterized by aggressive progression and limited treatment options, necessitating novel therapeutic strategies. Lysine-specific histone demethylase 1A (LSD1), a key…